Improvements in culture media and vitrification methods allowed the transfer of blastocyst stage embryos in an attempt for better selection of viable embryos 2. The selection of the best embryo to transfer during elective single embryo transfer (e-SET) is a major decision in the effort to reduce the rate of multiple pregnancies, while preserving live birth rate (LBR) 1. In conclusion, day 5 blastocysts in oocyte donation program have significantly higher CPRs and LBRs, and present shorter time to delivery, compared to day 6 blastocysts, regardless of embryo quality. A multivariate stepwise logistic regression indicated, that day 5 transfer was an independent factor for CPRs (OR 1.91 95% CI 1.43–2.54, P < 0.001) and LBRs (OR 2.26 95% CI 1.19–4.28, P = 0.01), regardless of embryo quality, compared to day 6. Day 5 blastocyst transfers had better embryonic development and significantly higher CPRs (34.24% vs. In a retrospective, multi-center study, with a single oocyte donation program, a total of 1840 frozen embryo transfers (FET’s) were analyzed, including 1180 day 5 blastocysts and 660 day 6 blastocysts transfers. The aim of this study was to compare clinical pregnancy rate (CPR) and live birth rate (LBR) between transfers of vitrified day 5 blastocysts and day 6 blastocysts in oocyte donation, blastocyst-only cycles. Data from frozen blastocysts transfers showed conflicting results, possibly due to heterogeneous patient population and embryo quality. If you have a normal embryo, your FET will be scheduled starting with your next cycle Day 1.The superiority of day 5 blastocysts compared to day 6 blastocysts in fresh cycle transfers was previously demonstrated and attributed mainly to endometrial asynchrony.
PGT results will now be available for which embryos are normal, abnormal and mosaic. Women who did a fresh transfer will now go back to their clinic for a blood pregnancy test (beta hCG) to see if their transfer was a success! Some women will do a day 6 fresh transfer if they didn’t have any embryos ready to transfer on day 5. If you’re genetically testing all embryos by PGT first, the embryos will be biopsied for testing and frozen to wait for PGT results to come back and schedule the FET.Īny slower developing embryos that make it to the blastocyst stage by day 6 will be biopsied (if you do PGT) and frozen. Some women will do a fresh transfer of an embryo on this day.Īny embryos that are a blastocyst by this day can also be frozen & used for a future FET cycle. You will be notified of how many embryos have made it to the blastocyst stage of development. Some patients will be scheduled for day 3 transfer but is not very common.
You may be updated on how the embryos are growing at this point. They will report how many eggs were retrieved, how many were mature, and how many fertilized Your clinic will call with fertilization results. The embryologist will count how many eggs were retrieved The egg retrieval will be scheduled for ~36 hours after your trigger shot time Take the trigger shot at a specific time set by your clinic
You will also have monitoring appointments so your doctor can track your follicle growth & assess when you will take your trigger shot Start stimulation medications (injections for 8-12 days on average)Ĭontinue stimulation medications as instructed by your clinic
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